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In 2015, EPFL researchers led by Melanie Blokesch published a seminal paper in Science showing that the bacterium responsible for cholera, Vibrio cholerae, uses a spring-loaded spear to literally stab neighboring bacteria and steal their DNA. They identified the spear mechanism to be the so-called "typ nike dunken low e VI secretion system" or chanclas yeezy T6SS, also used for interbacterial competition by m adidas yeezys any other bacteria.V. cholerae uses its T6SS to compete with other bacteria in its aquatic environment and acquire new genetic material, which the pathogen absorbs and exchanges against some parts of its own genome. This mode of "horizontal gene transfer" leads to rapid evolution and pathogen emergence. The pathogen V. cholerae has caused seven major cholera pandemics since 1817 and, according to current WHO data, still kills more than 100,000 people each year and infects up to 4 million others, mostly in poor or underdeveloped countries.Now, Blokesch's group has discovered the extent of DNA that V. cholerae can Banners in support of Prime Minister Nawaz Sharif have surfaced聽near the Judicial Academy in Islamabad where he is scheduled to appear before a joint investigation team (JIT) probing the Panama Papers case on Thursday.The J adidas samba sale IT investigating the case has summoned the PM to record his statement on Thursday, June 15. He has been asked to appear before the investigation panel with all documents relevant to the case.The banners emerged in聽the red-zone area of the federal capital, especially in the area surrounding the academy, according to聽Express News.The slogans inscribed messages in support of the premier, his daughter Maryam Nawaz as well as Punjab Chief Minister Shahbaz Sharif. Some聽read "move forward Nawaz Sharif, we (the masses) are with you."Panamagate: Imran asks Nawaz to step downThe premier's e adidas samba lder son Hussain Nawaz has alread adidas samba og y appeared five times before the JIT while younger Hassan Nawaz has appeared twice.On Monday, Pakistan Tehreek-e-Insaf chairman Imran Khan called upon the PM

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In a new study published inCell Host &amp; Microbe, scientists at La Jolla Institute for Immunology (LJI) compared the immune response of individuals who received older versus newer versions of the whooping cough vaccine. The unexpected findings may help explain the recent rise in whooping cough cases and point to potential targets for the next generation of vaccines.Whooping cough is a serious and sometimes life-threatening infectious disease caused by the highly <a href=https://www.adidas-yeezy.it>yeezy 350 contagious bacteriumBordetella pertussis. In 1948, the first whole-cell pertussis (wP) vaccine was made widely available, in which recipients were treated w yeezy ith an inactivated version of the entire bacterium. While extremely effective in producing immunity, the potent vaccine sometimes caused short-term side effects, dunk sb leading the United States to adopt an acellular pertussis (aP) vaccine in 1996. This vaccine contains only four proteins fromB. pertussis.Want more breaking news?Subscribe to Technology Networks鈥?daily newsletter, Punjab Chief Minister Shehbaz Sharif met Interior Minister Chaudhry Nisar Ali Khan on Wednesday and requested him not to make his party鈥檚 internal confl ugg fellboots ict public by holding a press conference,聽Express News聽reported.The chief minister held a meeting with his fellow Pakistan Muslim League (PML-N) leader at stanley cups the Punjab House and urged him to resolve the issues amicably, sources said. Sharif said the ongoing rift could be taken care of internally and there was no need to make it public.Shehbaz commended Nisar鈥檚 efforts for the party and told him that he was an important part of the PML-N.Media reports of Chaudhry Nisar鈥檚 resignation baseless: interior ministryThe interior minister said that his differences were based on principles and that he was not working for his own interests but for the party and the country.The sources said senior PML-N leaders were trying to convince Nisar not to go for a hard-hitting press conference and refrain from target adidas samba vegan ing the policies of his party鈥檚 leadership

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Tr nike dunk high iLink BioTechnologies has been awarded a Small Business Innovation Research (SBIR) Phase II grant of approximately $750,000 to continue its investigation of modified primers to improve the fidelity of PCR reactions. Phase I studies demonstrated that TriLink's modified primers not only significantly reduced products due to undesired priming, but also enhanced the formation of the desired amplicon in a number of different experiments. In the seco dunk low nd phase of the program, TriLink will look to further improve these Phase I study results by expanding the technology to offer聽solutions for qPCR, RT-PC yeezy slide R and multiplex PCR and qPCR. TriLink will also optimize protocols for scale up and automated synthesis, in preparation for commercialization of the technology in early 2007. This is the second Phase II grant TriLink has been awarded."We believe that this discovery has the potential to be a very important advancement in PCR technology," said Dr. Richard Hogrefe, CEO and President of TriLink. "Th Actor Leonardo DiCaprio, who is currently dating model Nina Agdal, is reportedly planning to marry her next year.This Olympic archer looks just like Leonardo DicaprioAccord adidas adidas samba ing to a source, the "low-key lovers" Di adidas campus Caprio and Agdal have "a secret wedding in the works" and he is looking forward to marry Agdal next spring, reports ac new balance bleu eshowbiz.com. PHOTO: JUSTJARED

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Isis Pharmaceuticals, and聽Alnylam Pharmaceuticals has announced that a key patent was issued by the United States Patent and Trademark Office (USPTO).The U.S. patent broadly covers certain chemical modifications of oligonucleotides used to intr dunks oduce "drug-like" properties in antisense oligonucleotides, including small interfering RNAs (siRNAs), the molecules that mediate RNA interference (RNAi). The issued patent is owned by Isis and is licensed exclusively to Alnylam for double-stranded RNAi therapeutic applications pursuant to the terms of their 2004 collaboration and license agreement."Our intellectual property estate continues to yield issued patents stemming from our pioneering efforts in the discovery and development of RNA-based therapies, including RNAi and other antisense mechanisms," said C. Frank Bennett, dunk sb Ph.D., Senior yeezy 350 Vice President, Research for Isis. "This new patent is particularly important for the emerging field of RNAi therapeutics, where our strategic alliance with A In his early morning Twitter rit new balance 991 ual, US President Donald Trump on Thursday retwee adidas campus rouge ted a meme of himself eclipsing former president Barack Obama.The meme captioned 鈥淭he best eclipse ever鈥? shows a ginning Trump moving in front of Obama 鈥?edited in black and white. pic.twitter.com/6XJxEg1gSs&mdash; Jerry Razor Travone鈩笍 (@JerryTravone) August 24, 2017Trump remained a harsh critic of Obama through out the latter's tenure. He floated theories against the former president including that of him being a Muslim and the "birth certificate" issue where he alleged Obama was not born in the US.Last week, the US president came under scrutiny for blaming "both sides" aft ugg hausschuhe er the violence in Charlottesville.聽Trump鈥檚 weak condemnation of the racist far-right set off a political firestorm across the US political spectrum. World leaders also criticised Trump鈥檚 response.

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An international team of researchers led by the University of British Columbia has made a scientific advance they hope will lead to the development of preventative treatments for multiple sclerosis (MS).In a study published today in PLOS Genetics, researchers found mutations in 12 genes believed to be largely responsible for the onset of MS in families with multiple members diagnosed with the disease."These genes are like a lighthouse illuminating where the root cause of MS is," said lead author Carles Vilari帽o-G眉ell, assistant professor in the UBC faculty of medicine's department of medical genetics and a Michael Sm dunk nike high ith Scholar.MS is a disease that affects the central nervous system, in which cells from the immune system attack and damage the nerve cells' protective sheath. The disease often results in disability and can have a significant impact on quality of life.For the study, researc nike dunken low hers sequenced all known genes in three or more MS patients from 34 families and examined nike high dunk the geneti LANDI KOTA ugg ultra mini L:Pakistani authorities have handed over four suspected Islamic State militants to Afghanistan on Tuesday.The suspected militants had crossed into Pakistan after being injured in a fight with the Afghan Taliban in the Nangarhar province and were later arrested from a hospital in Peshawar.Assistant political agent Landi Kotal Niaz Muhammad said the security forces had arrested the four injured Da鈥檌sh fighters from a hospital in Peshawar and later handed them over to the political administration in Khyber Agency.The suspected militants were identif ugg mini ied as Javed Khan, Niamtullah, Safiullah and Taaliman. All the militants belonged to Afghanistan鈥檚 Nangarhar district and had i campus adidas beige llegally crossed into Pakistan.鈥淧akistan will never let its soil be used against Afghanistan and today鈥檚 move is a gesture toward peaceful Afghanistan,鈥?he said.Published in The Express Tribune, February 8th, 2017.

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A breakthrough trial suggests that <a href=https://www.nike-dunk.it>dunk nike low MDMA-assisted therapy is both safe and effective for people with post-traumatic stress disorder (PTSD).The first Phase 3 trial of MDMA-assisted therapy for PTSD replicated and expanded on Phase 2 results indicating MDMA-assisted therapy may be an effective and cost-saving treatment for PTSD resulting from any cause. Nature Medicine is expected to publish the peer-reviewed paper detailing the results of the study sponsored by the Multidisciplinary Association of Psychedelic Studies (MAPS) and conducted by MAPS Public Benefit Corporation (MAPS PBC), a wholly-owned subsidiary of MAPS. In this first Phase 3 trial of any psyche yeezy 350 delic-assisted therapy, participants who received MDMA-assisted therapy reported a significant reduction dunk cacao in PTSD symptoms compared to those who received placebo with therapy (p<0.0001), successfully achieving the prespecified primary endpoint for the trial. In fact, 67% of the group who received MDMA, compared to 32% of the group LONDON:Manchester United centre-back Eric Bailly expects to return within two months after injuring his knee during his side's 4-0 Premier League defeat at Chelsea, he said on Tuesday."I wanted to thank you for all the messages of support that I received since the injury!" the Ivory Coast defender wrote on his official Facebook page. "I hope to be able to play again for United and The Elephants before 2 months, God willing. Thanks for always being there!"The message was accompanied by a picture of Bailly sitting in the passenger seat of a car at United's training ground, with his right leg in a brace.Michael Carrick the answer for clueless Jose MourinhoA close-season signing from Villarreal, Bailly limped off early in the second half at Stamford Bridge on Sunday, with Marcos Rojo coming on to take his place."He is injured and I'm afraid he's badly injured," manager Jose Mourinho said in his post-match pre new balance nere ss conference. "In his knee nb mujer , in the ligament area, he feels th nb balance at is really bad."Ne