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A Wyss Institute-led collaboration spanning four research labs and hundreds of miles has used the Institute鈥檚 organ-on-a-chip (Organ Chip) technology to identify the antimalarial drug amodiaquine as a potent inhibitor of infection with SARS-CoV-2, the virus that causes COVID-19.The Organ Chip-based drug testing <a href=https://www.nbbalance.de>new balance 9060 ecosystem established by the collaboration greatly streamlines the process of evaluating the safety and efficacy of existing drugs for new medical applications, and provides a proof-of-concept for the use of Organ Chips to rapidly repurpose existing drugs for new medical applications, including future pandemics. The research is reported inNature Biomedical Engineering.While many groups around the world have been testing existing drugs for efficacy against COVID-19 usin nb g cultured cells, it is well known that cells grown in a di adidas yeezy sh do not behave like the cells in a living human body, and many drugs that appear effective in lab studies do not work in patients. The Wyss team examined Your St adidas samba adidas ars TodayAries | March 20 鈥?April 18Making progress can be challenging but there鈥檚 always the rewarding sense of achievement that comes with it. However, it鈥檚 easy to forget that in the process of moving ahead, certain elements of the past must be left behind. That鈥檚 certainly the case now. Let these go. You won鈥檛 regret it.Taurus | April 19 鈥?May 19Planning ahead may make life easier. However, with so much in transition, even the simplest of arrangements will probably need to change, and change again. Knowing that, ensure whatever you organise is flexible enough you can rethink things if necessary. As important, discuss those plans with others from the outset.Gemini | May 20 鈥?June 20Now that both the Sun and your ruler Mercury are in the mos nb 530 t strategic porti ugg boots on of your chart, you鈥檒l realise that you鈥檙e better off leaving as many decisions as possible to others. While, ordinarily, you enjoy debating various options and shaping plans, steering clear of these is by far the best ch

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By studying nerve cells that originated in patients with a severe neurological disease, a University of Wisconsin-Madison researcher has pinpointed an error in protein formation that could be the root of amyotrophic lateral sclerosis.Also called Lou Gehrig's disease, ALS causes paralysis and death. According to the ALS Association, as many as 30,000 Americans are living with ALS.After a genetic mutation was discovered in a small group of ALS patients, scientists transferred that gene to animals and began to search for drugs that might treat those animals. But that approach has yet to work, says Su-Chun yeezy 500 Zhang, a neuroscientist at the Waisman Center at UW-Madison, who is senior author of the new report, published April 3 in the journal Cell Stem Cell.Zhang has nike dunk sb been using a different approach -- yeezy ciabatte studying diseased human cells in lab dishes. Those cells, called motor neurons, direct muscles to contract and are the site of failure in ALS.About 10 years ago, Zhang was the first in the wor Japan Airlines Co said on Monday it has begun screening passengers from the seven Muslim-majority countries affe nb 550 cted by the President Donald Trum adidas samba schuhe p's travel ban before th nb 550 eir departure for the United States.Airlines in Cairo asked to implement Trump travel ban -EgyptAirOfficials at Japan's second biggest carrier will contact the US Customs and Border Protection agency when passengers from those countries check in at the airport before departure to confirm whether they will be allowed entry, a spokesman for the airline said.

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Researchers have demonstrated that vehicle armor using composite metal foam (CMF) can stop ball and armor-piercing .50 caliber rounds as well as conventional steel armor, even though it weighs less than half as much. The finding means that vehicle designers will be able to develop lighter military vehicles without sacrificing safety, or can improve pr converse plateau otection without making vehicles heavier.CMF is a foam that consists of hollow, metallic spheres 鈥?made of materials such as stainless steel or titanium 鈥?embedded in a metallic matrix made of steel, ti nike dunkpanda tanium, aluminum or other metallic alloys. In this study, the researchers used steel-steel CMF, meaning that both the spheres and the matrix were made of steel.For the study, researchers manufactured a hard armor system consisting of a ceramic faceplate, a CMF core and a thin back plate made of aluminum jordan2 . The armor was tested using .50 caliber ball and armor-piercing rounds. The armor was tested with the rounds being fired at impact velocitie JAKARTA:Authorities have recovered body parts and debris in waters where an Indonesian plane carrying police went missing, officials said Sunday, raising fears over the fate of the flight's passengers and crew.Indonesian police plane with 15 on board goes missingThe M28 Skytruck plane carrying 13 people lost contact with air traffic control Saturday during a flight from Pangkal Pinang, Bangka Belitung province to Batam in the Riau Islands province in western Indonesia.Airplane seats and suitcases along with body parts were recovered by fishermen off Riau Islands Saturday afternoon rescue officials told AFP."We sent three body bags last night, the body new balance donna parts were not intact... they are now in the Bhayangkara hospital in Batam," said Bambang Soelistyo, the head of Indonesia's search and rescue agency.He added that search adidas samba rose and rescue efforts would continue for another week. Indonesia has a poor aviation safety record and ha adidas sambarose s experienced several air disasters recently.First plane arrives wi

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In an article published online in the journal of Circulation: Heart Failure the teram of collaborators from Scios Inc. in Fremont, Christ Hospital in Cincinnati, and Mediv adidas yeezys ation Inc. in San Francisco, discovered very low concentration of bioactive BNP in plasma obtained from patients with heart failure, and presented direct structural evidence for several proteolytically degraded forms of BNP in these patients. "Commercially available assays for immunoreactive BNP do not reflect the bioactivity of the natriuretic peptide system, since asics gel 1130 they measure yeezy 350 both unprocessed, inactive proBNP and mature BNP 1-32," says Eric Niederkofler, Ph.D., the principal investigator from Intrinsic Bioprobes. BNP is synthesized as a 108 amino acid propeptide and proteolytically processed to release an inactive 76 amino acid N-terminal fragment and bioactive mature BNP 1-32 into the bloodstream. "This is the first assay capable of detecting and quantifying BNP 1-32 alone. Furthermore, the assay allowed us to stu LAHORE:The Lahore High Court has provisionally removed the age limit of 24 years for getting admission to the five-year bachelor of law (LL adidas samba programmes in Punjab.On Thursday, a full bench of LHC headed by Chief Justice Mansoor Ali Shah issued the interim order on a petition challenging the age bar.The judges ruled that if candidates have already done their BA they will be considered in the LLB three-year programme. Anybody over and above the age of 24 years without holding a BA degree is provisionally eligible to apply for the five-year LLB pro stanley cup gramme.Death penalty: LHC rejects appeals of seven military court convictsThe court also constituted a commission headed by the Punjab advocate general and including one representative each of Pakistan Bar Council and P nb 550 unjab Bar Council, commissioner/district coordination officer and district police chief.The bench directed the commission to hold its first meeting on December 12 at 11 am to verify by carrying out physical inspections whether the

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Established by the The University of Melbourne at the Doherty Institute, the new Centre located in the Microbiological Diagnostic Unit Public Health Laboratory (MDU PHL) is home to state-of-the-art technology that utilises next-gener <a href=https://www.nike-dunk.es>nike high dunk ation DNA sequencing, which provides unparalleled speed and accuracy to genetically identify a yeezys nd track disease-causing microbes.Directed by The University of Melbourne鈥檚 Professor Ben Howden, Director of MDU PHL, and Associate Professor Tim Stinear, this new technology will enable more rapid diagnosis of infectious diseases, more timely identification of disease outbreaks and allow clinicians to make more informed therapeutic decisions.Professor Ben Howden said that aside from the technology, what made the Centre so powerful were its advanced, high-end computation capabilities.鈥淟ed by world-renowned bioinformatician Associate Professor adidas yeezy Torsten Seemann from the Victorian Life Sciences Computation Initiative, these capabilities allow us to use the large amoun KARACHI:A society cannot do without the contribution of the youth.Youth Employment Project (YEP) deputy project manager Qasim Naqvi said this during a youth convention, titled 鈥楽kills and Employment Opportunities for Youth鈥? organised by the Strengthening Participatory Organisation (SPO).The convention, held on Thursday at the main auditorium of the Memon Industrial and Technical Institute (Miti), was attended by over 500 participants, most of which were young women.The convention aimed at crea new balance 327 ting interaction between key stakeholders and jobless young men and women of Korangi. SPO, with the support of United Nations Development Programme (UNDP), has recently launched YEP in three different underprivileged areas of the city - Lyari, Sultanabad and Korangi.Youth Affairs Minister Abid Hussain Bhayo urged the young participants to acquire skill-based training for a better futur adidas campus grau e. 鈥淲e all have to make efforts for new balance rose a better and developed Pakistan,鈥?he said, adding that the provincial governm

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