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A regulator of gene expression, retinoid X receptor (RXR), can boost scavenging cells in their mission to clear the brain of dead cells and debris after a stroke, thus limiting inflammation and improving recovery, according to preclinical research led by Jarek Aronowski, MD, PhD, of The University of Texas Health Science Center at Houston (UTHealth).The discovery of RXR as a cleanup booster suggests that the molecule activating RXR could lead to discovery of a promising new therapeutic target.鈥淩XR could enhance the cleanup and reduce the injury to brain tissue caused by the toxic byproducts created by an ischemic stroke,鈥?said Aronowski, professor in the Department of Neurology at McGovern Medical School at UTHealth. 鈥淭his could be a clinically relevant target for improving recovery.鈥滱fter a stroke, there is a buildup of d air force 1 damen ead cells and debris in the brain, a toxic environment that leads to damaging inflammation. Phagocyt yeezy 700 ic immune cells, such as microglia and blood-derived macrop yeezy 500 hages, SYDNEY:An Australian politician has set fire to a river to draw attention to methane gas he says is seeping in adidas campus 00's to the water due to fracking, with the dramatic video attracting more than two millions views.Greens MP Jeremy Buckingham used a kitchen lighter to ignite bubbles of methane in the Condamine River in Queensland, about new balance 996 220 kilometres (140 miles) west of Brisbane.The video shows him jumping back in nb 993 surprise, using an expletive as flames shoot up around the dinghy."Unbelievable. A river on fire. Don't let it burn the boat," Buckingham, from New South Wales, said in the footage posted on Facebook on Friday evening, which has been viewed more than two million times.How Saudi Arabia turned its greatest weapon on itself"Unbelievable, the most incredible thing I've seen. A tragedy in the Murray-Darling Basin (river system)," he said, blaming it on nearby coal-seam gas mining, or fracking.Australia is a major gas exporter, but the controversial fracking industry has faced a public backl

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One in 25 patients with very low kidney function were ad nike airforce mitted to hospital with severe confusion and other cognitive-related symptoms a few days after being prescribed a common muscle relaxant.A new study from ICES Western, Western University and Lawson Health Research Institute has shown tha nike high dunk t patients with kidney dysfunction who were prescribed a high dose of the drug baclofen, were more likely to be admitted to hospital for disorientation and confusion, than those who weren't prescribed the drug. Their results are being published on November 9 in the high impact journal,JAMAand are being presented at the same time at the American Society of Nephrology meeting in Washington, D.C."When we looked at people with low kidney function (30 per cent or less) who received a high dose of baclofen from their prescriber, approximately one in 25 were being admitted to hospital with severe confusion, typically over the next few days, " said Dr. nike dunks low Amit Garg, Professor at Western's Schulich School of M SIALKOT:Minister for Water and Powe stanley-cup r Khawaja Asif said on Sunday the government was committed to resolving the energy crisis.Talking to APP at Pakistan Muslim League House, he said investment in power generation programmes had been prioritised.鈥淥ur goal is to eliminate load shedding by 2018,鈥?he said. The minister said the government had been taking steps to improve adidas original campus power generation.鈥淥ver the last two years, there has been a sizeable reduction in load shedding hours as a result of these efforts,鈥?he said.鈥淭he government was elected on the promise that it would resolve the energy c adidas samba risis and steer the economy towards growth and prosperity. We are committed to this,鈥?he said.鈥淲e have launched projects for short-term and medium term in the energy sector. This has had a stabilising effect on industrial production,鈥?he said.Asif said the federal government was also investing in improving means of communication in rural areas.鈥淲e want to improve living standards of residents of rural areas,鈥?

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Textbooks and popular science books claim <a href=https://www.nbbalance.de>newbalance schuhe with certainty that women are better at finding words and remembering words, but is this really a fact?鈥淲omen are better. The female advantage is consistent across time and life span, b yeezys 350 ut it is also relatively small鈥? says Marco Hirnstein, professor at The University of Bergen, Norway.Hirnstein is interested in how biological, psychological, and social factors contribute to sex/gender differences in cognitive abilities and what the underlying brain mechanisms are.Will the results finally settle pub debates on who鈥檚 better?"So far, the focus has mostly been on abilities, in which men excel. However, in recent years the focus has shifted more towards women", says Hirnstein.We thought Women were better 鈥?and they are!The origin of these sex/gender differences; nature versu nike dunks panda s nurture - and the potential consequences of these differences have been the subject of big societal debates. As in do men and women have different talents for different profess LAUSANNE/LONDON new balance rose /KARACHI:Pakistan鈥檚 middle-order batsman Asad Shafiq has said Pakistan will fare better tha nb balance n Sri Lanka in England as the Men in Green have more depth in their batting line-up as compared to the Islanders.England have so far outclassed Sri Lanka, winning the first Test by an innings and 88 runs and the second Test by nine wickets.Faith in cricket: Inzamam leads the way at Gaddafi skill campThe new-ball duo of Stuart Broad and James Anderson, ranked third and first in the world respectively, have ripped apart Sri Lanka at will but Shafiq feels Pakistan are better equipped to face them.鈥淥ur batting is more experienced as compared to Sri Lanka鈥檚 and we鈥檒l do better against England,鈥?Shafiq told reporters in Lahore. 鈥淲e鈥檝e more depth in our batting with seniors such as Younus Khan and skipper Misbahul Haq.鈥滱nd Shafiq says Pakistan are learning from the newbalance 9060 mistake of others. 鈥淲e鈥檙e watching what mistakes Sri Lanka are making and we鈥檙e using Duke balls in our practice.鈥滳ook can br

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Miami authorities now have a new tool to find the likely source of heroin, potentially opening new avenues to disrupt the nation鈥檚 opioid crisis.In a collaborative effort, researchers at the FIU International Forensic Research Institute (IFRI) and the University of Miami (UM) Rosenstiel School of Marine and Atmospheric Science have zeroed in on a unique component of heroin that could help determine the locations of origin converse plateau for individual batches.鈥淭he DEA wanted to know specifically whether elemental analysis could determine where heroin was coming from,鈥?said Joshua DeBord, a chemistry Ph.D. student at FIU who is a co-a new balance 574 uthor of the recent study validating the effectiveness of the new method. 鈥淚t鈥檚 helpful for them to develop intelligence from heroin that is seized.鈥滺eroin is one part of the opioid epidemic gripping the nation, claiming almost 13,000 lives in 2015, according to the U.S. Department of Health and Human Services. There are four regions around the globe known fo new balance f眉r herren r producing h U.S. musician Chris Cornell, who gained fame as the lead singer of Sound new balance 480 garden and later Audioslave, died on Wednesday in Detroit, the Associated Press reported on Thursday. He was 52.Cornell's family would be working closely with the medical examiner to determine the cause, the AP reported, citing a statement from representative Brian Bumbery. The Audioslave and Soundgarden lead singer's death was "sudden and unexpected", his representative Bumbery said.Seattle-born Cornell won two Grammy awards in 1994 with rock band Soundgarden. As the lead singer for Seattle-based Soundgarden, Cornell helped architect the 90's grunge rock mov new balance rose ement. He was also a Grammy award-w adidas campus wei脽 inning, Golden Globe nominated singer, songwriter, guitarist, composer and lyricist.David Rockefeller dies at 101In addition, Cornell became involved in philanthropy and started the Chris and Vicky Cornell Foundation to support children facing challenges, including homelessness, poverty, abuse and neglect.Cornell was still a w

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Much like a supply truck crossing the countryside, the misfolded proteins that dunk high nike damage neurons in Alzheimer's disease travel the "roads" of the brain, sometimes stopping and sometimes re-routing to avoid roadblocks, reports a study published in Science Advances by researchers at Van Andel Institute and University of Pennsylvania.The findings shed light on how tau proteins, which form tangled clumps that damage brain cells in Alzheimer's, move through the brain. The study also provides new insights into why some areas of the brain are more vulnerable to damage than other areas."While th yeezy e interconnected structure of the brain is essential to its function, these misfolded proteins commandeer that structure to tr yeezy boost avel through the brain and cause progressive degeneration," said Michael X. Henderson, Ph.D., an assistant professor at Van Andel Institute and corresponding author of the study. "By understanding how these proteins travel through the brain and what causes certain neurons to be at r KARACHI:The Secur adidas campus blu ities &amp; Exchange Commission of Pakistan (SECP) has issued State Life Insurance Corporation of Pakistan the window Takaful licence. Since its formation in 1973, State Life Insurance Corporation of Pakistan is playing its part as the country鈥檚 largest life insurance company, offering life and group insurance to millions of Pakistanis through its wide network of offi newbalance 574 ces across the nation. State Life Insurance Corporation of Pakistan is the only life insurance company in Pakistan rated AAA by the Pakistan Credit Rating Agency (PACRA). This rating is an endorsement of State Life鈥檚 outstanding financial stability and commitment to聽its obligations, and also proves that the company will continue serving its fellow Pakistanis under window Takaful.Published in The Express Tribune, August nb 530 27th, 2016.Like聽Business on Facebook, follow @TribuneBiz聽on Twitter to stay informed and join in the conversation.

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A growing number of people are suffering from hearing loss due to exposure to loud noises from heavy machinery, concerts, or explosions. As a result, scientists have been working to understand the mechanism behind how the damage to hearing actually occurs.Now, a team le af1 d by researchers at the University of Maryland School of Medicine (UMSOM) has published an online interac nike sb dunk tive atlas representing the changes in the levels of RNA made in the different cell types of ears of mice, after damage due to loud yeezy 350 noise. These changes in RNA levels are known as changes in 鈥済ene expression.鈥漁nce they determined the larger trends in gene expression following the damage, the UMSOM scientists then searched a database of FDA-approved drugs to find those that are known to produce opposite patterns of those caused by the noise. From this analysis, the research teams identified a handful of drug candidates that may be able to prevent or treat the damage, and ultimately preserve hearing.Their analysis was p LONDON:Senior British politicians have called for voter registration for the June 23 referendum on EU membership to be reopened after a government website crashed shortly before the deadline on Tuesday night, hampering some people's efforts to register.The deadline passed at midnight (2300 GMT), and half a million people registered online on the final day, according to a government website that provides data on the voter registration system.Staying in EU 'the British thing to do', says CameronBut at 11:35 pm, the Cabinet Of adidas samba adidas fice, the government department in charge of the issue, tweeted that it was aware of an issue with the website, which was due to unprecedented demand, and was working to resolve it.Minutes later, it tweeted an apology to those experiencing problems, urging them to keep trying as som adidas campus verdi e people were still getting through. Almost an hour after the official deadline, it twee stanley cup ted that the issue had been fixed, without specifying whether any applications received after midnig