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In everyday life, our tissues, for example skin and muscle, are stretched, pulled and compressed without causing damage to the cells or the DNA. A team of researchers led by Sara Wickstr枚m from the Max Planck Institute for the Biology of Ageing and the CECAD Cluster of Excellence at the University of Cologne and the Helsinki Institute for Life Sciences at the University of Helsinki has now discovered that cells protect themselves from such stres new balance nb 530 s by not only deforming the cell nuclei, yeezy 350 but also softening the genetic material itself.Prote chanclas yeezy ction of the genetic code within our DNA is critical for human health. Mutations in DNA lead to a large variety of diseases, such as developmental disorders or cancer. 鈥淢ost of our tissues contain tissue-specific stem cells, which are long-lived cells whose function is critical for tissue function and maintenance. Due to their long lifetime, it is critical that the genome of these cells is efficiently protected from mutations to prevent diseases such as MULTAN:Multan Mayor Naveedul Haq Araein vowed to beautify the city through an integrated master plan. As part of the plan, new fun parks would be constructed and plantation of trees and stanley cups vegetation adidas samba sale in public places would be ensured after clearing encroachments.The mayor said a facilitation centre was being set up in the city with the help of World Bank to facilitate the people in interacting with various government departments and agencies.He said the accountability process to monitor the performance of officials had been initiated while campaign against cleanliness and encroachment was also underway.Naveed maintained a list of 200 ghost employees working in Solid Waste Management had been prepared and action would be taken against them. He hinted at sealing shops and plazas for not removing encroachments outside their premises. He said he had already held consultations with traders' association before initiat adidas samba damen ing crackdown against it.In addition, the mayor had also prepared a strategy a

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The Caribbean was one of the last regions of the Americas to be settled by humans. Now, a new study published in the journal Science sheds new light on how the islands were settled thousands of years ago dunk nike low .Using ancient DNA, a team of archaeologists and geneticists led by researchers from the University of Copenhagen and the Max Planck Institute for the Science of Human History found evidence of at least three population dispersals t adidas yeezys hat brought people to the region.鈥淭he new data give us a fascinating glimpse of the early migration history of the Caribbean. We find evidence that the islands were settled and resettled several times from different parts of the American mainland鈥? says Hannes Schroeder, Associate Professor at the Globe Institute, University of Copenhagen, and one of the senior authors of the study.More data, more detailsThe researchers analyzed the genomes of 93 ancient Caribbean island new balance 480 ers who lived between 400 and 3200 years ago using bone fragments excavated by Caribbean a KARACHI:High level police tra newbalance nsfer and postings are on the card in Sindh. In this connection, Sindh IG AD Khawaja has written to the chief secretary to transfer six DIGs. Officials in Sindh government told The Express Tribune that Additional IG traffic Khadim Hussain Bhatti will be transferred and posted as Additional IG research, development and inspection. The recommendation sent from the IG office further said that Ghulam Sarwar Jamali, working as Additional IG admin Karachi range, is likely to be posted as DIG crime branch, Karachi.聽 Meanwhile, the name of Munir Ahmed Shaikh, DIG South, Karachi has been recommended for the post of DIG admin Karachi adidas campus noir and a senior police officer, Azad Khan, who is waiting for a posting, will replace Shaikh. Dr new balance hombre Jameel Ahmed, working as DIG traffic Hyderabad, is likely to be posted as DIG CIA Karachi range from where Sultan Khawaja has been transferred. However, Khawaja鈥檚 name has been recommended for DIG information technology, Sindh.Published in The E

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ChemAxon聽and聽FMC Corporation have announced global licensing of ChemAxon's complete product line and the switch over of FMC Agricultural Products Group's structure search platform to ChemAxon's JChem cheminformatics platform.Through the global acquisition of ChemAxon's toolkits FMC is able to implement cheminformatics platforms useful for insilico structure design, screening, property prediction and management. The migration of the structure search at FMC's Agricultural Products Group is the first step in this integration."FMC's APG Discovery Research has evaluated ChemAxon's products, JChem and Marvin, and found the products to be intuitive, easy to use, reliable, and scalable," said Dr. Ann Orth, Resea air force schwarz rch Director for FMC's Agricultural Products Group."In FMC's opinion, ChemAxon's tools are technically sound and are enterprise solutions. More importantly, the e dunks nike low valuation has, in FMC's opinion, shown that the search re yeezy damen sults from JChem Cartridge are more chemically precise and logical t LAHORE:The Punjab Information Technology Board (PITB) and Pakistan Stock Exchange (PSX) agreed in principle to sign a Memorandum of Understanding (MoU) to facilitate startups in raising equity from the capital market, marking a move adidas campus donna towards facilitating entrepreneurs in the country.This was stated by PITB Chairman Dr Umar S ugg hausschuhe aif on Friday during the 4th Roundtable Conference powered by TechHub.Saif said that this partnership would serve as an important step towards encouraging entrepreneurs seeking to raise investment locally, and would give a major boost to small and medium enterprises, the adidas samba schuhe IT industry and the national economy.He further informed that on signing the MoU both the parties would collaborate and endeavour to facilitate technological entrepreneurship in Pakistan and nurture an ecosystem for the growth of technology startups.Under the proposed MoU, the PITB would share its database of registered startups so that they can sign up on the online PSX Private Market.The launch of

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WHO today released REPLACE, a step-by-step guide for the elimination of industrially-produced trans-fatty acids from the global food supply.Eliminating trans fats is key to protecting health and saving lives: WHO estimates that <a href=https://www.nbbalance.de>nb every year, converse chucks trans fat intake leads to more than 500,000 deaths of people from cardiovascular disease.Industrially-produced trans fats are contained in hardened vegetable fats, such as margarine and ghee, and are often present in snack food, baked foods, and chanclas yeezy fried foods. Manufacturers often use them as they have a longer shelf life than other fats. But healthier alternatives can be used that would not affect taste or cost of food."WHO calls on governments to use the REPLACE action package to eliminate industrially-produced trans-fatty acids from the food supply,"said WHO Director-General, Dr Tedros Adhanom Ghebreyesus. "Implementing the six strategic actions in the REPLACE package will help achieve the elimination of trans fat, and represent a major victory in th Bollywood diva Anush adidas campus blanche ka Sharma, who will be seen opposite Shah Rukh Khan in their upcoming movie聽Jab Harry Met Sejal聽says romancing the superstar was quite easy and that he can even romance a microphone.Both of them came alo newbalance 530 ng with music director Pritam and film director Imtiaz Ali for the launch of the new song Haw adidas campus rose ayeina.First look of SRK and Anushka's next Bollywood project is outAsked about how was it romancing Shah Rukh third time, on-screen, Anushka said, "Extremely easy! There is a genuineness in his eyes that we all can see - that reflects on-screen. In my opinion, he can even romance a microphone."To this, Shah Rukh replied, "As long as you are holding the mic, darling!"The evening started with a live performance by Pritam where he sang the song live and went on to show it on the big screen.Two of the songs of the film Radhaa and Beech Beech Mein has already been released and gained popularity.The trailer of 'Harry Met Sejal' reminds us of some iconic films and we're not complai

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A new research study has found that midazolam 鈥?a sedative used before surg adidas yeezy ery to make patients relaxed and sleepy 鈥?is associated with a greater risk of heart damage when used at night.The circadian clock affects more than our sleep鈥搘ake cyclesProfessor Tobias Eckle, the senior author of the study, yeezy is an expert in chronotherapy. In previous research, he illustrated that proteins beneficial for heath health are expressed more strongly at different times of day and that intense light can promote heart healing.What is chronotherapy?Chronotherapy aims to optimize medical treatments by taking the body鈥檚 nike dunk high circadian (sleep鈥搘ake) rhythms into account during their design or administration. SHABQADAR:A power feeder was inaugurated in Lower Mohmand Agency. A ceremony was held at Ghallanai Power Grid Station on Saturday to launch the project.MNA Bilal Rehman inaugurated the power feeder.While speaking on the occasion, Rehman said he has spent Rs230 million on enhancing power supply schemes in the agency.鈥淭he second priority will be to ensure the provision of pure drinking water to the entire agency,鈥?he said. 鈥淭his has been done to overcome the problems faced by the public and provide ease to loc stanley online shop als.鈥滱ccording to Rehman, a new power supply feeder will be installed in Prang Ghar to overcome power trippi newbalance 574 ng and load-shedding in the agency.Published in The Express Tribune, August ugg boots f眉r damen 21st, 2016.

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Sci new balance herren entists at The Scripps Research Institute (TSRI) have determined how two proteins help create organelles, or specialized subunits yeezy 700 within a cell, that play a vital role in maintaining cell health. This discovery opens the door for research on substances that could interfere with the formation of these organelles and lead to new therapies for cancer.The study, published online ahead of print on December 2, 2012, by the journal Nature Structural &amp; Molecular Biology, focuses on the structure and function of the two proteins, ATG12 and ATG5. These proteins need to bond correctly to form an organelle called the autophagosome, which acts like a trash bag that removes toxic materials and provides the cell with nutrition through recycling.鈥淥ur study focuses on one of the big mysteries i yeezy slides n our field,鈥?said Takanori Otomo, the TSRI scientist who led the effort. 鈥淭hese proteins are linked, but no one has explained why clearly. We鈥檙e very excited to have determined the structure of these link NEW YORK:New York's famed Empire State Building will go dark on Wednesday in tribute to the 41 people killed and 239 wounded in a suicide attack at Istanbul's main international airport.The tribute new balance uomo has become a somber ritual following a string of high-profile attacks, including bombings in Paris last November, in Belgium in March and the Orlando nightclub shooting earlier this month.US condemns 'heinous' Istanbul attack, pledges support for TurkeyThe landmark building said it would darken its wor ugg ld-famous lights in sympathy for the victims and those affected by Tuesday's attack.Turkey and the CIA have pointed the finger of blame at the Islamic State extremist group based in Iraq and Syria. There has been no claim of responsibility.Istanbul airport attack: IS prime suspect after suicide bombers kill 41Witnesses described scenes of terror and panic as the attackers began shooting indiscriminately and then blew themselves u new balance blanche p at the entrance to Ataturk airport, one of Europe's busiest avia